About PRA and HTN
The Renin, PRA & Hypertension App uses plasma renin activity (PRA) testing to guide antihypertensive drug selection with the goal of effective blood pressure control with as few agents as possible. It is based on the...
The Renin, PRA & Hypertension App uses plasma renin activity (PRA) testing to guide antihypertensive drug selection with the goal of effective blood pressure control with as few agents as possible. It is based on the concept that hypertension is sustained by an excess of either body sodium-volume (V) or plasma renin (R), and that all antihypertensive drugs are either anti-V or anti-R.
A low PRA indicates V hypertension, treatment with an anti-V drug, and (if no compelling indications) subtraction of anti-R drugs. A medium to high PRA indicates R hypertension, treatment with an anti-R drug and then, if renin is blocked and BP not controlled, adding an anti-V drug.
Apr 14, 2021
Version 2.0.0
- The upper limit of the normal range of PRA was reduced to 4.5 from 6.5 ng/ml/hr in accordance with recent observations.
- Direct Renin ranges were provided for the treatment algorithm.
- Apps recommendations associated with greater BP reduction (Clin Trans Sci 2021; 14:617).
- App improvements
Previous Versions
Here you can find the changelog of PRA and HTN since it was posted on our website on 2016-10-18 17:16:54.
The latest version is 2.0.0 and it was updated on 2024-04-23 10:57:46. See below the changes in each version.
PRA and HTN version 2.0.0
Updated At: 2021-04-14
Changes: Apr 14, 2021
Version 2.0.0
- The upper limit of the normal range of PRA was reduced to 4.5 from 6.5 ng/ml/hr in accordance with recent observations.
- Direct Renin ranges were provided for the treatment algorithm.
- Apps recommendations associated with greater BP reduction (Clin Trans Sci 2021; 14:617).
- App improvements
PRA and HTN version 1.1
Updated At: 2013-02-20
Disclaimer
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